“The best evidence shows that half of all the clinical trials ever conducted and completed on the treatments in use today have never been published in academic journals. Trials with positive or flattering results, unsurprisingly, are about twice as likely to be published — and this is true for both academic research and industry studies.
If I toss a coin, but hide the result every time it comes up tails, it looks as if I always throw heads. You wouldn’t tolerate that if we were choosing who should go first in a game of pocket billiards, but in medicine, it’s accepted as the norm. In the worst case, we can be misled into believing that ineffective treatments are worth using; more commonly we are misled about the relative merits of competing treatments, exposing patients to inferior ones.”
These quotes are from an article that appeared Feb. 1, 2013 in the NY Times: trick-coin.pdf
In academia, we like to think the we practice so-called “evidence based medicine.” Unfortunately, it turns out the evidence that we have is flawed. It comes either from industry, which has a vested interests in keeping damaging studies about their products from us, and from journal editors who find it necessary to publish only studies with positive results.
Thus, the evidence based medicine that we like to tout, is biased and flawed because it is predicated on data obtained from “Medicine’s Trick Coin.”
Evidence based medicine? Who’s evidence?!